10/29/2023 0 Comments Grapefruit and medications![]() ![]() If you are taking any of those three statins, make sure to discuss grapefruit consumption with your doctor. There are three statins that are of concern here: simvastatin (Zocor), lovastatin (Mevacor), and atorvastatin (Lipitor) ( 2, 3, 4). Not all statins use that same enzyme, though. That makes the drug more powerful than it is intended to be ( 1). Grapefruit contains compounds that inhibit this enzyme. That’s because these drugs metabolize in the gut, via a certain enzyme called CYP3A. Grapefruit and grapefruit juice can interact with some cholesterol medications, most notably, statins. ![]() Which ones? Read on to find out which heart medications may interact with grapefruit! Grapefruit and Cholesterol Medication That’s why it’s so important to avoid grapefruit when you take certain heart medications. This can lead to blood pressure that’s too low, medication toxicity, and (if untreated) potentially death. While grapefruit is certainly healthy, and even good for your heart, it also adversely interacts with many heart medications. Have you ever been told to avoid grapefruit or grapefruit juice when you started a new medication? Or maybe you’ve seen it on the bottle: a warning not to consume grapefruit while taking that med? And isn’t grapefruit healthy? The article Grapefruit and Heart Medications is for educational purposes only, and is not a substitute for individualized and qualified medical advice. Disclaimer: Always consult your doctor or pharmacist regarding any concerns you may have about your medications or side effects.
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